Treatment of otitis media with Sofradex is the correct use of effective ear drops. Drops for ears Sofradeks - instructions for use Sofradeks for inhalation instructions for use

Drops Sofradex is a drug for topical use in ENT practice, which has a pronounced anti-inflammatory and antibacterial effect.

The drug Sofradex has a broad spectrum bactericidal and antibacterial effect due to gramicidin and framycetin, and is active against such gram-positive and gram-negative microorganisms.

The anti-inflammatory, anti-allergic and antipruritic effect is exerted by a glucocorticoid - dexamethasone. As a result of instillation into the eye, pain, burning sensations decrease, photophobia, lacrimation and other symptoms characteristic of pathological processes caused by the corresponding pathogens occur.

Clinical and pharmacological group

A drug with antibacterial and anti-inflammatory action for topical use in ophthalmology and ENT practice.

Conditions of sale from pharmacies

Can buy with a doctor's prescription.

Price

How much does Sofradex cost in pharmacies? The average price is at 350 rubles.

Composition and form of release

Sofradex drops are intended for administration to the eyes and ears. Therefore, “Sofradex ear drops” are the same as “Sofradex eye drops”.

• Framycetin (5 mg) is an antibiotic that actively affects the bacteria of staphylococcus, dysentery and other harmful microorganisms (except for those that can live in an airless space).
• Gramicidin (50 mg) - acts as additional support for framycetin. The component itself is not expensive, but necessary for the complex treatment of bacterial and infectious diseases.
• Dexamethasone (500 mg) is a special hormone required to suppress inflammatory processes. In addition to its main function, it helps relieve allergic reactions, swelling and itching.
• Additional substances that do not have a medical effect.

pharmachologic effect

The drug Sofradex is combined and has the following therapeutic effects:

1. Antibacterial action.
2. Anti-inflammatory action.
3. Anti-allergic effect.

Drops and ointment Sofradex contain two antibiotics - framycetin and gramicidin, from the group of aminoglycosides. These antibiotics effectively destroy a wide range of pathogenic microorganisms that cause infectious and inflammatory diseases of the ears and eyes. Framycetin destroys a large number of gram-positive bacteria, including Staphylococcus aureus, which is an opportunistic microbe, often causes inflammatory lesions of various organs, and it is rather difficult to cure. Also, framycetin has a detrimental effect on the main gram-negative microorganisms - Escherichia coli, dysentery, Proteus, etc. Resistance to this antibiotic is developing very slowly. Framycetin does not destroy streptococci, fungi and microbes that can live in an oxygen-free environment (anaerobic). The second antibiotic of Sofradex, gramicidin, increases the spectrum of action of framycetin, especially well against staphylococci that are difficult to treat.

The third component of Sofradex ointment and drops is the glucocorticoid hormone dexamethasone, which has the property of suppressing the inflammatory reaction, reducing the production of substances that stimulate inflammation, and reducing the degree of capillary wall permeability. In addition, dexamethasone has the ability to suppress allergic reactions and itching. Dexamethasone also relieves puffiness, improving nasal breathing, hearing and vision.

When injected into the eyes, Sofradex relieves pain, eliminates burning, lacrimation and photophobia. And the introduction of the drug into the ears allows you to eliminate skin redness, soreness, itching, burning sensation in the external auditory canal and the feeling of a stuffy ear.

Indications for use

The indications are the following bacterial diseases:

1. External catarrhal or purulent.
2. Bacterial (inflammation in the surface of the eye).
3. Inflammation of the eyelid and its edges.
4. Keratitis and iridocyclitis (inflammatory changes in the cornea, iris and ciliary body of the eye).
5. Scleritis or episcleritis (when itself or the outer layers of the opaque membrane of the eye are inflamed).
6. Infected with bacteria eczematid skin of the eyelids (characterized by the appearance of itching, burning and wetness on the skin of the eyelid).

Contraindications

Before starting treatment, you should carefully read the instructions for the drug, since Sofradex drops have a number of contraindications and restrictions for use:

• keratitis caused by the herpes virus;
• glaucoma (increased intraocular pressure);
• perforation of the tympanic membrane;
• pregnancy and the period of breastfeeding;
• individual intolerance to the components of the drug;
• diseases of the eyes and ear of a viral and fungal nature - in this case, the drug will simply not be effective;
• tuberculosis;
• trachoma;
• violation of the integrity of the mucous membrane of the eye;
• children under 2 years old.

With special care, treatment with Sofradex is prescribed to children of younger preschool age, since prolonged and uncontrolled use of drops can lead to the development of systemic side effects, in particular from the adrenal glands.

Appointment during pregnancy and lactation

To date, there have been no experiments aimed at establishing the negative effect of the antibiotic on the course of pregnancy and child development. It is known that the drug is able to diffuse through the placental barrier and into breast milk. Therefore, pregnant patients and women during lactation are prohibited from therapy with this medication.

If there is an urgent need for use, breastfeeding should be suspended. Important: the active ingredients included in the composition negatively affect the intestinal microflora of the child and can lead to the formation of extensive pathological processes.

Dosage and method of administration

As indicated in the instructions for use, Sofradex ear drops should be instilled into the external section of the ear canal, 2-3 drops. 3-4 times a day, or - can be laid with a gauze swab moistened with a solution.

Drops in the ears of Sofradex are used for no more than 7 days, with the exception of cases of visible positive dynamics. It should be remembered that GCS mask hidden ongoing infections, long-term use of antimicrobial drugs contributes to the development of resistant flora and superinfections.

For instillation into the eyes

In case of eye diseases: with a mild course of the infectious process, 1-2 drops of the drug are instilled into the conjunctival sac of the eye every 4 hours. In the case of a severe infectious process, the drug is instilled every hour. As the inflammatory phenomena decrease, the frequency of instillation of the drug decreases.

Side effect

As a rule, the drug Sofradex is well tolerated by patients. After instillation of the drug in persons with increased individual sensitivity, local side effects may develop:

• burning;
• pain;
• impaired sensitivity (dullness of hearing or blurred vision).

These side effects are not dangerous and do not require discontinuation of drug treatment and disappear on their own in 15 minutes.

Overdose

An overdose of Sofradex is possible if drops are used for more than 7 days and its symptoms are caused by addiction to dexamethasone. In this case, there is an increase in all the above-described side effects of impaired adrenal function.

At the first sign of an overdose, drug treatment is canceled and a doctor is consulted. If necessary, specialists will prescribe symptomatic treatment.

special instructions

Local GCS should never be used in patients with eye hyperemia of unknown eliology, because inappropriate use of the drug can lead to significant visual impairment.

With prolonged use of the drug, as well as with long-term use of other antimicrobial agents, it is possible to develop superinfections caused by microorganisms resistant to the drug, including fungi.

Prolonged instillation of the drug into the eye can lead to thinning of the cornea with the development of its perforation, as well as to an increase in intraocular pressure. Treatment with drugs containing corticosteroids should not be repeated or prolonged without regular monitoring of intraocular pressure, eye examination for the development of cataracts or secondary infections.

The duration of drug use should not exceed 7 days, except in cases of obvious positive dynamics of the disease, because long-term use of GCS, which is part of it, can mask latent infections, and long-term use of antimicrobial components can contribute to the development of a stable flora.

Framycetin sulfate, which is part of the drug, is an antibiotic from the aminoglycoside group, which are characterized by the development of nephro- and ototoxic effects when used systemically or applied topically to an open wound or damaged skin. These effects are dose-dependent and are increased in renal or hepatic impairment. Although the development of these effects was not observed when the drug was instilled into the eyes, one should take into account the possibility of their occurrence in the case of topical application of high doses of the drug in children.

Patients who temporarily lose vision clarity after instilling the drug in the eye are not recommended to drive a car or work with complex equipment, machine tools or any other complex equipment that requires clear vision immediately after instilling the drug.

The bottle must be closed after each use. Do not touch the eye with the pipette tip. After opening the bottle, the drug should be used within 1 month.

Interaction with other drugs

Framycetin sulfate should not be used together with other antibiotics that have ototoxic and nephrotoxic effects (streptomycin, monomycin, kanamycin, gentamicin).

The eyes are affected by many harmful factors. Infections, allergic reactions and polluted environments are common causes of their inflammation. At the same time, visual acuity suffers, the eyes turn red, the person experiences itching, burning and pain. The drug "Sofradex" will help to cope with such symptoms. Eye drops are recognized as one of the most effective in inflammatory processes of various etiologies, but it is necessary to take into account contraindications and strictly follow the instructions.

Release form

"Sofradex" is supplied in dark glass vials with a dropper dispenser. The drug has one form of release - drops, which is the most convenient type of medicine for the eyes. The medication is packed in a small cardboard box and always comes with instructions.

Healing composition

The composition of "Sofradex" (eye drops) includes several active ingredients and excipients. The main healing ingredients are:

• the antibiotic gramicidin;
• glucocorticosteroid dexamethasone;
• aminoglycoside framycetin sulfate.

Additional substances necessary for the formation of drops and enhancing the action of the main ones include:

• sodium citrate;
• ethanol;
• sodium chloride.

Eye drops "Sofradex" contain gramicidin, therefore it is forbidden to combine them with other medicines containing an antibiotic. If such a need arose, then full supervision by a doctor is required.

Indications for use

The combined medication "Sofradex" has found wide application both in ophthalmology and in ENT practice. Drops are often prescribed by otolaryngologists for various forms of otitis media. The components that make up the product effectively eliminate itching, quickly neutralize pain, relieve an excessive reaction to light, remove watery eyes and relieve other symptoms of eye inflammation.

In ophthalmic practice, Sofradex is often prescribed. Eye drops indications for use are as follows:

• barley;
• eczema of the eyelids;
• blepharitis, when the inflammatory process affects the lower edge of the eyelids;
• conjunctivitis of various types;
• keratitis;
• iridocyclitis;
• allergic manifestations of a seasonal nature, for example, a reaction to plant pollen, as well as medicines, food, etc.

The medicine has a visible bactericidal effect, and also acts as an anti-allergic and anti-inflammatory agent.

Restrictions on use and absolute contraindications

It is imperative to study the annotation before using Sofradex. The instructions for use indicate all possible restrictions on the treatment with this drug, as well as contraindications and side effects. So, "Sofradex" is not prescribed if the patient:

• tuberculosis;
• a violation of the integrity of the eye shell was diagnosed;
• keratitis;
• glaucoma;
• pregnancy;
• hypersensitivity to drug components;
• age up to two years.

In childhood, a medication is allowed for use, but if the baby is not yet seven years old, then the treatment should be strictly under the supervision of a specialist. Ophthalmologists warn that if the dosage is violated, the recommended therapy time is exceeded, then side effects can be provoked, the main of which is disruption of the adrenal glands.

Side effects of Sofradex eye drops

As shown by patient reviews, treatment is usually not accompanied by adverse reactions. On the contrary, unpleasant symptoms disappear quickly, the inflammatory process is effectively eliminated, and with it the itching, redness and burning sensation in the eyes disappear. However, sometimes side reactions still occur, which are expressed in the following:

• tingling in the eyes;
• slight itching immediately after instillation;
• decreased visual acuity (usually temporary, quickly passes);
• a veil before the eyes and a cloudy gaze.

Doctors warn that in individual cases, systemic negative manifestations may occur. These include the following symptoms:

• damage to the optic nerve;
• if the microflora of the eye is disturbed, which is possible with uncontrolled use of the drug, then there is a risk of fungal disease;
• thinning of the membrane of the eye.

As the patient reviews show, unwanted symptoms that bother in a mild form usually go away on their own after 15-20 minutes. But experts advise not to drive immediately after using the drops and refrain from working with mechanisms that require extreme concentration. It is necessary to wait about an hour and make sure that there are no harsh reactions. If there are serious complications or suspicions of them, then the drug should be canceled and consult an ophthalmologist.

"Sofradex": instructions for use

The doctor can prescribe individual treatment. If there are no special recommendations, then you can follow the instructions, which says that:

• instillations (eye instillations) are carried out every 4-6 hours if the condition is mild;
• you can bury it every hour in the first few days if the condition of the eyes is severe;
• 1-2 doses are allowed to drip into each conjunctival sac.

The frequency and duration of the procedures depends on the degree of the disease and the severity of the symptoms. It is important to gradually reduce the number of instillations - as the inflammatory process goes away. But experts warn that the maximum duration of treatment should not exceed seven days.

If it becomes necessary to use "Sofradex" (eye drops) during pregnancy, then it is necessary to weigh the possible risks and expected benefits. Clinical trials on this kind of patients have not been carried out, but it is known that the active substances penetrate in small quantities into the blood, so there is a possibility of their penetration through the placental barrier.

Breastfeeding mothers may be prescribed Sofradex eye drops. But at the same time, it is recommended to temporarily stop breastfeeding and use infant formula.

Use in childhood

Sofradex is quite effective and efficient against inflammatory eye diseases. Eye drops are not prescribed for children under the age of two due to the presence of a strong antibiotic. For older children, therapy can be indicated in individual cases and only on the recommendation of an ophthalmologist. In this case, the doctor calculates the dosage based on the severity of the symptoms, the general condition of the child and his age.

Non-specific application

Drops are often prescribed not only for inflammatory eye diseases. With otitis media, they have a healing effect. If you are worried about the pain in the ear caused by inflammation of the ear canal, then it is necessary to instill 2-3 doses up to 4 times a day. Sometimes the doctor may recommend that to relieve the condition, insert a cotton swab dipped in Sofradex solution into the ear. The total duration of therapy should not exceed seven days.

Drugs similar in action

Sometimes the drug is not suitable for the patient and must be changed. It is worth considering that there are no similar drugs for active substances, however, there are drugs that are similar in therapeutic effect.

How to replace "Sofradex" (eye drops):

• Dexon. The medicinal components are dexamethasone sodium phosphate and neomycin sulfate. It is not used in the therapy of children under the age of 18.
• "Tobradex". The drug is based on dexamethasone and tobramycin. The main ophthalmic characteristics are the same.
• "Dexa-Gentamicin". The drug eliminates the cause of inflammation and relieves unpleasant symptoms.
• Flixal. The active ingredient is ofloxacin. It is used in the treatment of adults and children, and the dosage is the same in both cases. The doctor only changes the number of instillations and individually sets the course of treatment.
• "Garazon". The main active ingredients are gentamicin and betamethasone. It is not used for the treatment of children under seven years of age. You also need to be careful when prescribing to patients with severe myopathy and diabetes mellitus.
• "Albucid". At the heart of the therapeutic component is sulfacetamide. For the treatment of children and adults, it is necessary to use a different concentration and do not forget about strict adherence to the instructions.

Not everyone is satisfied with the price of Sofradex eye drops. Cheap analogs cannot always solve the problem, but under certain indications they will completely replace the original. Among the most demanded and effective is "DexaTobropt". Drops cost, depending on the place of purchase, from 150 to 260 rubles and are also prescribed for inflammatory eye diseases. However, it is necessary to take into account age restrictions and contraindications.

How much is

Sofradex is relatively inexpensive. Eye drops can be purchased for 250-450 rubles, depending on the region of residence and place of purchase. However, not everyone thinks the cost is affordable, so you have to look for a replacement. Funds with a similar spectrum of action can be purchased at a price of 150 rubles, which is essential for many. However, it is necessary to understand that it is not always possible to replace a medicine with another, because each has its own active ingredients, contraindications and reception features.

Only an ophthalmologist can prescribe "Sofradex" or its analogue, taking into account the main diagnosis, associated problems, the patient's age and well-being.

Expert opinion

Doctors know that the drug is combined and consists of two potent antibiotics at once. Therefore, as practice shows, the drug has a pronounced anti-inflammatory effect, relieves signs of complications that occur during an allergic reaction in the eyes. The medication is often prescribed, because it has very few contraindications. If the patient strictly adheres to the recommendations, then the signs of the disease pass very quickly, and the side effects do not bother.

Of course, sometimes the drug may not be suitable for a particular patient, because it contains strong components. However, unpleasant symptoms can be short-term, in this case, observation and continuation of therapy is important. If the side reactions are very pronounced, then there is an individual intolerance. The doctor will not prescribe the drug if there are compelling contraindications, therefore, Sofradex will not cause persistent health disorders.

Drug with antibacterial and anti-inflammatory action for topical use in ophthalmology and ENT practice

Active ingredients

Framycetin sulfate (framycetin)
- (in the form of sodium metasulfobenzoate) (dexamethasone)
- gramicidin (gramicidin)

Release form, composition and packaging

Eye and ear drops in the form of a transparent, almost colorless solution, with the smell of phenylethyl alcohol.

Excipients: lithium chloride, sodium citrate, citric acid monohydrate, phenylethanol, ethanol 99.5%, polysorbate 80, water d / i.

5 ml - dark glass bottles (1) complete with a dropper - cardboard packs.

pharmachologic effect

Framycetin sulfate is an antibiotic from the aminoglycoside group, it has a bactericidal effect. It has a wide spectrum of antibacterial action, is active against gram-positive microorganisms, including Staphylococcus aureus, and most clinically significant gram-negative microorganisms (Escherichia coli, Diznteria bacillus, Proteus, etc.). Ineffective against steptococci. Does not affect pathogenic fungi, viruses, anaerobic flora. The resistance of microorganisms to framycetin sulfate develops slowly. Gramicidin - has a bactericidal and bacteriostatic effect, expands the spectrum of antimicrobial action of framycetin due to its activity against staphylococci, since it also has an anti-staphylococcal effect.

Dexamethasone - GCS, which has a pronounced anti-inflammatory and desensitizing effect. Dexamethasone suppresses inflammatory processes, inhibiting the release of inflammatory mediators, migration of mast cells and reducing capillary permeability. When instilled in the eyes, they will reduce pain, burning sensation, lacrimation, and photophobia. When instilled in the ears, it reduces the symptoms of the external ear (skin redness, pain, itching, burning sensation in the external auditory canal, a feeling of ear congestion).

Pharmacokinetics

When applied topically, systemic absorption is low.

Framycetin sulfate can be absorbed through inflamed skin or open wounds. Upon entering the systemic circulation, it is rapidly excreted by the kidneys unchanged. T 1/2 of framycetin sulfate is 2-3 hours.

When taken orally, dexamethasone is rapidly absorbed from the gastrointestinal tract. T 1/2 is 190 min.

Indications

Bacterial diseases of the anterior segment of the eye.

- conjunctivitis;

- keratitis (without damage to the epithelium);

- iridocyclitis;

- sclerites, episclerites;

- infected eczema of the skin of the eyelids;

- otitis media of the external ear.

Contraindications

- increased individual sensitivity to any component of the drug;

- viral or fungal infections, tuberculosis, purulent inflammation of the eyes, trachoma;

- violation of the integrity of the corneal epithelium and thinning of the sclera;

- herpetic keratitis (treelike corneal ulcer) (possibly an increase in the size of the ulcer and a significant deterioration in vision);

- glaucoma;

- perforation of the tympanic membrane (penetration of the drug into the middle ear can lead to the development of an ototoxic effect);

- pregnancy and lactation;

- infants.

Carefully: young children (especially when prescribing the drug in large doses and for a long time - the risk of developing systemic effects and suppression of adrenal function).

Dosage

When eye diseases: at easy course of the infectious process instill 1-2 drops of the drug into the conjunctival sac of the eye every 4 hours. In case of development severe infectious process the drug is instilled every hour. As the inflammatory phenomena decrease, the frequency of instillation of the drug decreases.

When : instill 2-3 drops 3-4 times / day, a gauze swab moistened with a solution can be placed in the external auditory canal.

The duration of use of the drug should not exceed 7 days, except in cases of obvious positive dynamics of the disease (GCS can mask hidden infections, and prolonged use of the antimicrobial components of the drug will contribute to the development of a stable flora).

Side effects

Allergic reactions usually delayed type, manifested by irritation, burning sensation, pain, itching, dermatitis.

When long-term use of topical corticosteroids it is possible: an increase in intraocular pressure with the development of a symptomatic complex of glaucoma (damage to the optic nerve, a decrease in visual acuity and the appearance of visual field defects), therefore, with more than 7 days of use of drugs containing glucocorticosteroids, intraocular pressure should be measured regularly; the development of posterior suppcapsular cataract (especially with frequent instillation); thinning of the cornea or sclera, which can lead to perforation; accession of a secondary (fungal) infection.

Overdose

Long-term and intensive local use can lead to systemic effects. Treatment is symptomatic.

If the contents of one vial (up to 10 ml of solution) are swallowed, serious side effects are unlikely to develop.

Drug interactions

Framycetin sulfate should not be used together with other antibiotics that have ototoxic and nephrotoxic effects (eg, monomycin, kanamycin, gentamicin).

special instructions

With prolonged use of the drug, as well as with long-term use of other antimicrobial agents, it is possible to develop superinfections caused by microorganisms resistant to the drug, including fungi.

Prolonged instillation of the drug into the eye can lead to thinning of the cornea with the development of its perforation, as well as to an increase in intraocular pressure. Treatment with drugs containing corticosteroids should not be repeated or prolonged without regular monitoring of intraocular pressure, eye examination for the development of cataracts or secondary infections.

Local GCS should never be used in patients with eye hyperemia of unknown eliology, because inappropriate use of the drug can lead to significant visual impairment.

Framycetin sulfate, which is part of the drug, is an antibiotic from the aminoglycoside group, which is characterized by the development of nephro- and ototoxic effects when used systemically or applied topically to an open wound or damaged skin. These effects are dose dependent and are increased by both renal and / or renal. Although the development of these effects was not observed when the drug was instilled into the eyes, the possibility of their occurrence should be taken into account in the case of topical application of high doses of the drug in children.

The duration of use of the drug should not exceed 7 days, except in cases of obvious positive dynamics of the disease, because long-term use of GCS, which is part of it, can mask hidden infections, and long-term use of antimicrobial components can contribute to the development of a stable flora.

Influence on the ability to drive vehicles and control mechanisms.

Patients who temporarily lose vision clarity after instilling the drug in the eye are not recommended to drive a car or work with complex equipment, machine tools or any other complex equipment that requires clear vision immediately after instilling the drug.

Storage conditions and periods

Store at a temperature not exceeding 25 ° C. Keep out of the reach of children. Shelf life 2 years. Do not use after the expiration date indicated on the package.

The instructions for the Sofradex eye drops indicate that they treat inflammatory and bacterial processes in the eyes, ears and nose and bring a lot of problems to patients.
The excruciating pains, constant discomfort do not make it possible to live and work fully. Sofradex - drops that have a detrimental effect on bacteria and have an anti-inflammatory effect.

Benefit and harm

With a combination drug that helps to quickly get rid of an incipient infection.

The drops are able to treat itching and infections caused by dirty hands. They show high efficiency in the treatment of otitis media, blepharitis, conjunctivitis and eczema of the eyelid skin.

The benefits of drops have been proven many times. Therefore, if the ophthalmologist decided to prescribe this particular drug, you should not refuse in any case.

In many Internet sources you can find information about the dangers of Sofradex. It is possible if the patient is not familiar with the contraindications to the medicine, uses the medicine uncontrollably, or does not follow the doctor's recommendations on dosage.

As a rule, the harm of a medicine can be seen with prolonged use. Side effects can include:

• the occurrence of irritation;
• dermatitis;
• pain in the eye area;
• itching and burning;
• increased intraocular pressure, which contributes to the development of glaucoma;
• bringing the cornea and sclera to thinning;
• the occurrence of a fungal infection.

If these side effects occur, do not draw conclusions about the dangers of instilling Sofradex. The drug may have been misused.

Indications for use

Sofradex is one of those drugs that actively fight inflammatory and infectious eye diseases.


Thanks to its anti-inflammatory, antibacterial and anti-allergic action, the first steps of the disease retreat are visible on the second day of the disease.

Uncontrolled use of the drug is prohibited, since there are a number of contraindications that can harm the body and cause a lot of complications.

Sofradex is available in the form of a glass or plastic bottle with a volume of 5 ml, packed in a cardboard container. Inside the package, for ease of use, there is a lid with a dispenser.

The composition of Sofradex is represented by additional components, the presence of 2 antibiotics and a corticosteroid, which are the main active substances of the drug:

• framycetin - in an amount of 5 mg / 1 ml;
• gramidicin - 0.05 mg / 1 ml;
• dexamethasone - 0.5 mg / 1 ml.

They have an anti-inflammatory and antibacterial effect, which guarantees one hundred percent fight against various harmful microorganisms. The most common of which are: staphylococcus, streptococcus, E. coli.

Thanks to dexamethasone, the patient can get rid of a number of unwanted symptoms: itching sensations, tearing, pain.

Indications and contraindications for use

The anti-inflammatory and antibacterial action of the drug allows it to be used to treat a number of ophthalmic problems, as well as in otolaryngology for the treatment of such diseases:

• conjunctivitis;
• scleritis;
• uveitis;
• keratoconjunctivitis;
• iridocyclitis;
• blepharitis;
• infected eyelid eczema;
• otitis externa in chronic and acute form (bactericidal).

Sofradex is prescribed strictly as directed by the attending physician. Independent use is strictly prohibited, since it has a number of contraindications and side effects.

1. With intolerance to the components of the drug.
2. During the course of such diseases as: tuberculosis, inflammatory processes with purulent accumulation, trachoma, diseases of the cornea of \u200b\u200ba viral and fungal nature.
3. With damage to the cornea and glaucoma. If it is impossible to refuse the drug, a consultation with a specialist is recommended before using it.
4. Perforation of the tympanic membrane.
5. The period of bearing and feeding the child.
6. Babies.

The use of drops for young children is allowed in very rare cases and implies complete control by the doctor over the treatment process.

When treating, it is worth remembering that the wrong dosage can provoke the occurrence of the side effects mentioned above.

If these symptoms occur, you must immediately notify your doctor. The drug may not be suitable for your body and needs to be replaced.

Dosage for adults and duration of treatment

The eyes are vital organs, and the slightest non-compliance with the dose of the drug can lead to a drop in vision, or blindness.

So, Sofradex belongs to those drugs that must be used strictly according to the doctor's prescription.

1. In case of mild bacterial infection - each eye is instilled with 1-2 drops at intervals of 4 hours.
2. In severe form - 1-2 drops every hour. If, after using the drops, the patient noticed an improvement, the interval between drops should be increased.
3. During otitis media - the drug is instilled in 2 drops four times a day. After instilling the drug, a cotton turunda is inserted into the ear canal.

The duration of the drug is a week. If during the specified time the patient did not show relief, it is recommended to re-examine, perhaps the diagnosis was wrong.

The fact can take place as a result of non-compliance with the requirements, which will lead to an addiction of the body. In this case, there may be side effects and disruption of the adrenal glands.

Video

Be sure to carefully read the instructions for the drug.

Use of the drug in children

Drops can be used for children as the main active agent in the treatment of otitis media, ocular inflammation and rhinitis. The use of drops for babies up to a year should be monitored by a pediatrician.

The duration of treatment is no more than 5 days. This is due to the fact that it contains 2 antibiotics, which can negatively affect the child's immunity.

However, practice shows that there is such a fact, and Sofradex is still prescribed as the main drug in the fight against bacterial diseases.

When using the medicine, it must be remembered that it has a toxic effect and, if used incorrectly, can harm the child:

• in the treatment of otitis media, it is recommended to apply a dosage of 1-2 drops three times a day in each ear;
• in the treatment of inflammatory processes of the eyes, the number of similar instillations can be increased up to 7 times a day;
• with a decrease in inflammatory processes, the number of instillations should be reduced;
• in the treatment of rhinitis, the recommended number of drops is 2-3 four times a day.

When using drops for young children, it is advisable to dilute them with saline. Compliance with the doctor's recommendations is a prerequisite for treatment.

Eye drops for the treatment of conjunctivitis

The drug effectively fights conjunctivitis, since its composition is aimed at fighting harmful bacteria.


Bacterial conjunctivitis, which manifests as eye inflammation, is best treated. The source of infection with bacterial conjunctivitis lies in poor personal hygiene and a weakened immune system.

For the treatment of conjunctivitis, the drug is instilled into each eye in 2-3 drops every 3 hours until the patient's general condition improves. When treating with drops, a slight burning sensation and discomfort may occur.

If other symptoms are present, the patient should inform the attending physician. Perhaps the drops are not suitable for your body, they will be replaced with another drug (analogue).

Topical treatment for bacterial conjunctivitis will be more effective the sooner treatment is undertaken.

Sofradex should be used with caution in the treatment of bacterial conjunctivitis in young children.

Appointment for adenoids

The effectiveness of treatment depends on the correct use of the drug. In order for the droplets to be injected correctly, the patient needs to lie down and not toss and turn.

This is necessary so that the drug gets in as accurately as possible and does not flow out of the nostrils. When injected into the nose, it should drain over the inflamed surface of the pharyngeal tonsil.

Treatment regimen:

1. From 1 to 10 days - 4 drops must be instilled into each nasal passage. The frequency of instillation is 3 times a day.
2. From 11 to 15 days - the drug is instilled 2 times a day, 2 drops.
3. From 16 to 20 days - Sofradex is administered once a day, 2 drops.

The practice of treating the disease shows that the first positive effect of the drug is observed in the first ten days.

The described scheme can be changed by the doctor and is not fundamental. For each patient, in accordance with the individual characteristics of the organism, its own effective dose can be selected.

During treatment with Sofradex, the patient's nasal breathing returns to normal, edema is relieved.

Treatment of adenoids in children should be under the supervision of a specialist, since there is a risk of unpleasant complications.

Instilling drops in the ear

Sofradex is effective in the fight against otitis media and other inflammatory processes in the ear. They have antibacterial, anti-inflammatory and anti-allergenic effects.

Has a detrimental effect on harmful bacteria and other focal diseases in the ear area. The first use of the drug guarantees minimization of pain, reduction of redness and removal of irritation in the ear.

Ear drops or ointment are used for the following ear diseases:

• otitis media of the external ear in acute and chronic form;
• a bacterial infection of the ear canal.

In case of ear diseases, the use of Sofradex is advisable provided that the tympanic membrane is intact, otherwise, negative consequences for the body are possible.

ROUSSEL INDIA SANOFI-AVENTIS Aventis Pharma Limited Sanofi India Limited

Country of origin

India

Product group

Sense organs / sight, hearing /

Drug with antibacterial and anti-inflammatory action for topical use in ophthalmology and ENT practice

Release forms

• 5 ml - dark glass bottles (1) complete with a dropper - cardboard packs.

Description of the dosage form

• Eye and ear drops in the form of a transparent, almost colorless solution, with the smell of phenylethyl alcohol.

pharmachologic effect

The combined preparation has antibacterial, anti-inflammatory and anti-allergic effects. Included in the drops, gramicidin and framycetin provide an effect against Staphylococcus spp., Streptococcus spp., Pathogens of anaerobic infections and other microorganisms. Dexamethasone is an active GCS. When instilled in the eyes, it reduces pain, burning sensation, lacrimation, photophobia.

Special conditions

It is recommended to control intraocular pressure during treatment. The duration of admission should not exceed 7 days, except in cases of obvious positive dynamics of the disease, because long-term use of GCS, which is part of the composition, can mask latent infections, and long-term use of antimicrobial components can contribute to the emergence of a stable microflora. A long intensive course can have a systemic effect. Framycetin, an aminoglycoside antibiotic, is ototoxic, especially when used in high doses and in patients with renal and / or hepatic insufficiency. Patients using the drug for the treatment of eyes during the period of treatment should be careful when driving vehicles and engaging in other potentially hazardous activities that require increased concentration of attention, speed of psychomotor reactions and good vision (possibly "blurred" vision).

Composition

• framycetin sulfate 5 mg gramicidin 50 μg dexamethasone (in the form of sodium metasulfobenzoate) 500 μg Excipients: lithium chloride, sodium citrate, citric acid monohydrate, phenylethanol, ethanol 99.5%, polysorbate 80, water d / i.

Sofradex indications for use

• Bacterial diseases of the anterior segment of the eye. - blepharitis; - conjunctivitis; - keratitis (without damage to the epithelium); - iridocyclitis; - sclerites, episclerites; - infected eczema of the skin of the eyelids; - otitis media of the external ear.

Sofradex contraindications

• - increased individual sensitivity to any component of the drug; - viral or fungal infections, tuberculosis, purulent inflammation of the eyes, trachoma; - violation of the integrity of the corneal epithelium and thinning of the sclera; - herpetic keratitis (treelike corneal ulcer) (possibly an increase in the size of the ulcer and a significant deterioration in vision); - glaucoma; - perforation of the tympanic membrane (penetration of the drug into the middle ear can lead to the development of an ototoxic effect); - pregnancy and lactation; - infants. With caution: young children (especially when prescribing the drug in large doses and for a long time - the risk of developing systemic effects and suppression of adrenal function).

Sofradex side effects

• Allergic reactions are usually of a delayed type, manifested by irritation, burning, pain, itching, dermatitis. With prolonged use of topical corticosteroids, it is possible: an increase in intraocular pressure with the development of a symptomatic complex of glaucoma (damage to the optic nerve, a decrease in visual acuity and the appearance of visual field defects), therefore, with more than 7 days of use of drugs containing glucocorticosteroids, intraocular pressure should be measured regularly; development of posterior supracapsular cataract (especially with frequent instillation); thinning of the cornea or sclera, which can lead to perforation; accession of a secondary (fungal) infection.

Storage conditions

• keep away from children
• store in a dark place

Information provided